Season 10 of Diablo 4 arrives on September 23, 2025, bringing sweeping changes to boss encounters, loot mechanics, and drop rates. With this update, Blizzard has overhauled boss mechanics, revamped loot tables, and introduced new Mythic and Chaos Uniques, making endgame farming more rewarding and strategic than ever. Whether you’re targeting specific Uniques or planning optimized farm routes, this guide breaks down the latest Season 10 boss loot tables, highlighting everything from Bartuc, Lord of Chaos, to World Bosses.

Season 10 Boss Updates & Mechanics

Season 10 introduces major changes to boss mechanics to make fights more dynamic and rewarding:

· Invulnerability Phases Reworked: Lair Bosses no longer become fully invulnerable at health thresholds. Instead, shields appear at 2/3 and 1/3 HP, which can be broken in 5 seconds to skip the old invulnerability phase.

· 10-Second Rule: Invulnerability mechanics don’t trigger in the first 10 seconds, ensuring smoother openings.

· Bartuc, Lord of Chaos: The new Infernal Hordes boss follows the same mechanics, adding chaotic portals and multi-phase combat for skilled DPS players.

These updates reward high-damage builds and make boss fights less frustrating, while loot drop rates have increased for Mythic and Unique Diablo 4 items across the board.

Types of Bosses in Season 10

Boss Type Boss Name

Initiate Lair Boss Echo of Varshan

Initiate Lair Boss Grigoire, The Galvanic Saint

Initiate Lair Boss Urivar

Initiate Lair Boss The Beast in the Ice

Initiate Lair Boss Lord Zir

Greater Lair Boss Duriel, King of Maggots

Greater Lair Boss Harbinger of Hatred

Greater Lair Boss Echo of Andariel

Exalted Lair Boss Belial, Lord of Lies

Infernal Hordes Bartuc, Lord of Chaos

Each boss has unique loot pools, drop rates, and summoning requirements.

Bartuc, Lord of Chaos – Season 10 Highlight

Bartuc returns from Diablo 2 as the new Infernal Hordes boss. Encounter him at the end of Infernal Hordes, facing chaotic portals, AoE attacks, and invulnerability phases.

Bartuc Loot Table (Torment 1+):

· Chaos Armor – Guaranteed above Torment 3

· Unique Chaos Perks – Guaranteed

· 75x Burning Aether – Guaranteed

· 4x Scroll of Restoration – Guaranteed

· ~7000 Obducite – Guaranteed

· ~425 Infernal Warp – Guaranteed

· ~15M Gold – Guaranteed

· 440,000 Gem Fragments – Guaranteed

· Unique & Legendary Gear – Guaranteed

· Cosmetic Reward – TBD

Summon Requirements: Torment 1+, Infernal Hordes Compass (from Seasonal Reputation, Helltide Chests, or World Bosses).

Initiate & Greater Lair Boss Loot Tables

Urivar: Drops Diablo IV materials like Abhorrent Heart, Mythic Uniques such as Neseken, the Herald (4.5%), and Uniques like Paingorger’s Gauntlets (Moderate). Cosmetic rewards are guaranteed.

Grigoire, The Galvanic Saint: Offers Mythic Uniques (2.25%), Uniques such as Endurant Faith (Moderate), and the Demonbinder Mount Armor cosmetic.

The Beast in the Ice: Drops Mythic and Uniques including Fists of Fate, Kilt of Blackwing (High), and Skull Torch cosmetic reward.

Echo of Varshan: Offers boots, gloves, and amulets with moderate to high rarity, and the Flesh-weld Rod Trophy cosmetic.

Lord Zir: Uniques like Vox Omnium (Moderate) and Orphan Maker (High) are farmable, with guaranteed Diadem of the Ancient Helm cosmetic.

Greater Lair Bosses like Duriel, King of Maggots and Harbinger of Hatred drop Mythic and Legendary items at higher rates, including Godslayer Crown, Azurewrath, and Banished Lord’s Talisman.

Echo of Andariel: Focused on diverse classes with moderate to high drop rates for weapons, armor, and amulets, along with the Smoldering Brimstone Mount cosmetic.

Exalted Lair Boss – Belial

Belial is the apex boss of the ladder:

· First Unique: Guaranteed from chosen Lair Boss pool

· Ancestral Unique: Guaranteed

· Mythic Unique: Highest chance among all bosses

· Extra Unique: +33% per additional party member

· Cosmetic Reward: Guaranteed

Belial requires defeating other Lair Bosses and collecting Betrayer’s Husk to access his Exalted Lair.

Infernal Hordes & Fell Council

Infernal Hordes is a wave-based survival mode, culminating in the Fell Council fight. Rewards include:

· Class-specific Uniques

· Mythic Uniques

· Legendary Aspects (e.g., Fortress, Spirit Bond)

· Crafting resources from Burning Aether

Recommended difficulty: Torment 1+ with Infernal Compass for summoning.

World Bosses

World Bosses are large-scale public encounters, spawning in regions like:

· Crucible (Fractured Peaks)

· Saraan Caldera (Dry Steppes)

· Seared Basin (Kehjistan)

· Fields of Desecration (Hawezar)

· The Cauldron (Nahantu)

Loot includes Spoils Caches, Scattered Prisms, and boss summoning materials.

Pinnacle Boss – Echo of Lilith

The ultimate challenge in Diablo 4’s endgame, Echo of Lilith offers:

· Resplendent Spark (first kill)

· Unique Mount

· Cosmetic Titles

· High-tier crafting rewards

Final Thoughts

Diablo 4 Season 10 is the most loot-focused season yet, with Mythics and Chaos Uniques more accessible than ever thanks to revamped drop rates and targeted boss pools. Whether you’re diving into Infernal Hordes for Bartuc’s Chaos Armor or climbing the Boss Ladder for exclusive cosmetics, Season 10 ensures that every grind feels more rewarding.

If you want to maximize your loot efficiency, plan your routes carefully, gather summon materials ahead of time, and prepare high-burst builds to cut through shields quickly.